Eating disorders and extreme weight conditions (i.e.: underweight- Anorexia (AN), overweight/obesity-Bulimia Nervosa (BN)/Binge Eating Disorder (BED) Mental and Behavioural Disorders
Conditions
Interventions
Participants are randomly allocated to two different interventions:
1. Treatment as usual (TAU, which is Cognitive Behavioral Therapy [CBT])
2. TAU + Playmancer (a therapeutic videogame to improve emo
patients with Bulimia Nervosa (BN)/Binge Eating Disorder (BED) and obesity or overweight receive 16 weekly session of CBT treatment in outpatient premises. The Playmancer intervention consists of nine
Sponsors
Hospitalet de Llobregat
Eligibility
Sex/Gender
Female
Inclusion criteria
Inclusion criteria: 1. Female gender 2. Age 18-60 3. Eating disorder patients must be diagnosed following DSM-5 criteria 4. Eating disorder patients must present a BMI (Body mass index) = 18.5 or BMI = 25 5. Healthy control individuals must be normoweight and present no psychiatric/neurological condition
Exclusion criteria
Exclusion criteria: 1. History of medical chronic disease, neurological condition, learning disorder or intellectual disabilities that could be affecting cognitive functioning 2. Use of psychostimulant or any unprescribed drug during the last 6 months. Changes in medication regime, such as type of drug and dose 3. Male gender 4. For patients with obesity/overweight, to have previously suffered from Anorexia Nervosa 5. For patients with Anorexia Nervosa, to have previously suffered from Bulimia Nervosa or Binge Eating Disorder or presented overweight/obesity 6. In patients with obesity, to suffer from endocrine obesity (excepting hypothyroidism under treatment) and to not present and eating disorder
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Primary outcome measures at baseline (cross-sectional study): differences between the three groups: AN-underweight, BN/BED-overweight/obesity, healthy controls (HC) Primary outcome measures for the intervention (randomized clinical trial): differences in changes between the two intervention groups in two different extreme weight conditions. The two clinical groups are assessed at three different timepoints: 1) baseline before starting treatment (pre), 2) after 4 weeks of treatment coinciding with the end of the Playmancer intervention (Post 1) and 3) at the end of treatment (Post 2). The HC is only part of the baseline assessment. Assessment battery: 1. Emotion regulation and impulsivity measures (Pre-Post 1- Post 2): UPPS -P Conducta Impulsiva Scale (Whiteside y Lynam , 2001), Escala de dificultades en la Regulación Emocional Escala (Ders; Gratz y Roemer , 2004), Cuestionario de Regulación Emocional (ERQ; Gross & John, 2003), Yale Food Addiction Scale (YFAS; Gearhardt et al., 2009) 2. Neuropsychological measures. Pre-Post 1-Post 2: Stroop Colours and Words Test (SCWT; Stroop, 1935; Golden, 1978), Iowa Gambling Task (IGT): (IGT; Bechara et al., 1994), Continuous Performance Test-II (CPT-II; Conners & Staff, 2000). Pre: Subtest de Vocabulario de la Wechsler Adult Intelligence Scale-III (WAIS-III) 3. Neurophysiological measures (EEG) (Pre-Post 1-Post 2). Three paradigms: emotion regulation task, craving regulation task, emotion go no go task. Event-related potentials will be analyzed for the different paradigms | — |
Secondary
| Measure | Time frame |
|---|---|
| 1. Clinical measures (Pre, Post 1, Post 2): Symptom CheckList-90 items-Revised (SCL-90-R; Derogatis et al., 1977), Eating Disorders Inventory- 2 (EDI-2; Garner, 1991), Screening diagnóstico SCID-I para trastornos mentales del Eje I (First, 1996) 2. Personality scale (Pre): Temperament and Character Inventory-Revised (TCI-R; Cloninger, 1999) 3. Weight, height and Body Mass Index (Pre, Post 1, Post 2): TANITA MC-180 Multifrecuencia.(TANITA 8, Bioimpedancia) | — |
Countries
Spain
Outcome results
None listed