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Study of alternative regimens of high dose induction therapy for systemic vasculitis

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ISRCTN
Registry ID
ISRCTN30771772
Enrollment
Unknown
Registered
2002-02-05
Start date
2001-02-01
Completion date
Unknown
Last updated
2015-01-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Systemic vasculitis Circulatory System Systemic vasculitis

Interventions

At entry the patients will be randomised to either: 1. The HiCy3 regime (six tapering pulses of cyclophosphamide over 3.5 months, with the first pulse being 1.6 g/m^2) 2. The spCy regime - standard pu

Sponsors

Arthritis Research Campaign (ARC) (UK)
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: 1. Patients with newly diagnosed systemic vasculitis 2. Patients with a major recent flare and total previous dose of cyclophosphamide less than 70 g

Exclusion criteria

Exclusion criteria: Not provided at time of registration

Design outcomes

Primary

MeasureTime frame
Not provided at time of registration—

Secondary

MeasureTime frame
Not provided at time of registration—

Countries

United Kingdom

Outcome results

None listed

Source: ISRCTN (via WHO ICTRP) · Data processed: Feb 4, 2026