Topic: Oral and Gastrointestinal
Conditions
Interventions
GIC modified with chlorhexidine.
GIC with 5% chlorhexidine, applied once and left in place.
Sponsors
University of Leeds (UK)
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1. Patients will be >=60 yrs (females and males) 2. Patients will have at least one lesion of root caries, which requires operative intervention. 3. Patients who are willingly to provide signed informed consent. 4. Patients who are willing to follow the research schedule for the period of the study.
Exclusion criteria
Exclusion criteria: 1. Patients with no natural teeth. 2. Patients currently having antibiotic therapy or within 4 weeks of completion of a course of therapy with antibiotics. 3. Patients who are currently receiving or who have had radiotherapy of the head and neck region within the last 12 months. 4. Patients who are currently using or who have used toothpastes and/or mouthwashes containing chlorhexidine within the last 4 weeks. 5. Patients who have active periodontal disease which is likely to require treatment such as root surface debridement (RSD) during the study. 6. Patients who have any condition (including an allergy to chlorhexidine) which could be expected to interfere with the patient?s safety during the study. 7. Patients who demonstrate an inability to comply with study procedures.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Reduction of bacteria in plaque samples; Timepoints: 6 months post treatment | — |
Secondary
| Measure | Time frame |
|---|---|
| 1. Reduction of bacteria in plaque samples; Timepoints: 1 and 3 months post treatment 2. Reduction of bacteria in saliva samples; Timepoints: 1 and 3 month post treatment 3. Reduction of bacteria in saliva samples; Timepoints: 6 months post treatment 4. Survival rate of restorations; Timepoints: 6 months post treatment 5. Treatment delivery acceptability by dental therapists; Timepoints: Baseine, and at 1, 3 and 6 months post treatment 6. Treatment delivery acceptability by patients; Timepoints: Baseline and at 1, 3 and 6 months post treatment | — |
Countries
United Kingdom
Outcome results
None listed