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To assess whether addition of pyriproxyfen to long-lasting insecticidal mosquito nets increases their durability compared to standard long-lasting insecticidal mosquito nets

To assess whether addition of pyriproxyfen to long-lasting insecticidal mosquito nets increases their durability compared to standard long-lasting insecticidal mosquito nets: protocol for a cluster randomized study

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ISRCTN
Registry ID
ISRCTN30634670
Enrollment
1500
Registered
2014-08-13
Start date
2014-03-01
Completion date
Unknown
Last updated
2018-09-10

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Durability of mosquito nets Infections and Infestations

Interventions

Two villages will take part in the trial. The compounds within each village will be randomly allocated to receive one of two types of bednets on a 50/50 basis Control bednet: Olyset net with 2% w/w pe

Sponsors

Durham University (UK)
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: 1. Village residents who sleep in a bed 2. Those that provide their informed consent to participate in the trial

Exclusion criteria

Exclusion criteria: 1. Non-residents 2. Residents who do not sleep in a bed 3. Those that do not provide their informed consent

Design outcomes

Primary

MeasureTime frame
Bio-efficacy is either measured as: 1. Percentage adult female mortality 24 hours after exposure to netting 2. Percentage of viable offspring (1st or 2nd stage larvae) relative to the control group This will be recorded immediately after net distribution and at 6, 12, 18, 24, 30 and 36 months.

Secondary

MeasureTime frame
Proportion of nets in 'poor' condition, defined as: 1. Those that are not long enough to be tucked under the mattress 2. Torn or badly damaged 3. Has more than five holes (finger-width, approximate diameter 2 cm) All outcomes will be measured at 0 weeks, 6, 12, 18, 24, 30 and 36 months.

Countries

Burkina Faso

Outcome results

None listed

Source: ISRCTN (via WHO ICTRP) · Data processed: Mar 17, 2026