Lung cancer Cancer Lung cancer
Conditions
Interventions
Intervention arm:
1. MSCT-scanning for the early detection of lung cancer immediately at time of randomisation and 4 times annually
2. Further assessment of suspicious
Sponsors
German Cancer Research Centre (Deutsches Krebsforschungszentrum)
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1. Age 50-69 2. Smoking history of at least 40 pack-years 3. If under the age of 60, current smokers or ceased smoking within the last five years 4. Able to complete a self-administered epidemiology questionnaire providing details on smoking history, family history of lung and other cancers (if any), occupational history and previous illnesses 5. Agree to be randomised to screening with annual low dose spiral CT plus smoking cessation counseling or only smoking cessation counseling 6. Have signed an informed consent form
Exclusion criteria
Exclusion criteria: 1. History of lung cancer or other malignancy (except basal cell carcinoma) 2. History of a disease that would preclude surgical as well as medical treatment of lung cancer 3. Other serious illness that would reduce life expectancy to less than 10 years
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Mortality from lung cancer at 5 and 10 years. | — |
Secondary
| Measure | Time frame |
|---|---|
| No secondary outcome measures | — |
Countries
Germany
Outcome results
None listed