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HD grid vs circular mapping catheter for assessment of pulmonary vein reconnection

Comparative study of Advisor HD grid versus circular mapping catheters in assessment of pulmonary vein isolation following previous ablation for atrial fibrillation

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ISRCTN
Registry ID
ISRCTN30513341
Enrollment
130
Registered
2021-04-08
Start date
2021-05-01
Completion date
Unknown
Last updated
2024-07-15

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Atrial fibrillation Circulatory System Arrhythmia

Interventions

The procedure will be performed by a Consultant Cardiologist or Specialist Registrar with experience of catheter ablation for AF. All patients recruited will have a clinical indication for AF ablation

Sponsors

Brighton and Sussex University Hospitals NHS Trust
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: 1. Documented recurrence of AF 2. One previous AF ablation 3. Suitable for clinically indicated catheter ablation 4. Aged >18 years

Exclusion criteria

Exclusion criteria: 1. Pregnancy or planning pregnancy 2. Current enrolment in another investigational trial 3. Pulmonary vein isolation on mapping at baseline

Design outcomes

Primary

MeasureTime frame
Radiofrequency energy time to isolate reconnected pulmonary veins (measured in seconds during the procedure)

Secondary

MeasureTime frame
1. Mapping times for both catheters (HD Grid and Circular mapping catheter) (measured in seconds during the procedure using the Ensite electro-anatomical mapping system) 2. Ability to correctly identify the gaps in pulmonary veins (recorded during the procedure by analysis of electroanatomical maps by cardiac electrophysiologist) 3. Location of isolation of pulmonary vein (recorded during procedure using electroanatomical maps) 4. Duration of ablation procedure (recorded during the procedure) 5. Any procedural complication (pericardial effusion, bleeding >2 units, phrenic nerve palsy and other) (recorded during and after the procedure via routine clinical follow up within 30 days)

Countries

England, United Kingdom

Outcome results

None listed

Source: ISRCTN (via WHO ICTRP) · Data processed: Feb 4, 2026