Topic: Dementias and neurodegeneration
Conditions
Interventions
Participants have either been diagnosed with a form of dementia or are healthy volunteers (control group). Participants are asked to carry out a number of memory tests to examine:
Stud
Sponsors
University of the West of England, Bristol
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1. A diagnosis made within the previous 18 months by a consultant psychiatrist of either probable Alzheimer’s disease according to the NINCDS-ADRDA criteria (McKhann et al, 1984) or probable vascular dementia according to the NINDS-IREN criteria (Román et al, 1993) or a mixed form of these 2. Mild levels of cognitive impairment (e.g. MOCA score over 12 or equivalent score on an alternative assessment tool) 3. The capacity to consent to be part of the research 4. Sufficient communication skills to be able to take part in the research Control group: Healthy volunteers recruited from Join Dementia Research (JDR) register, students and staff at the University of the West of England
Exclusion criteria
Exclusion criteria: 1. They have a significant history of pre-morbid psychiatric problems 2. They have a diagnosis of dementia with Lewy Bodies (McKeith, 2002) or frontal-temporal dementia (Snowden, Neary and Mann (2002) 3. If deficits in short-term memory are not a primary cause of disability
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Current primary outcome measures as of 11/01/2017: Study A: the mean number of dementia and non-dementia words recalled Study B: the mean number of behaviour statements recalled (central or peripheral and positive or negative) Study C: the mean number of high threat and low threat dementia statements recalled There was only one timepoint to this study, the research appointment lasted up to an hour and the method was to simply count up the number of correct words/behaviours/statements recalled or recognised by each participant Previous primary outcome measures: Number of words, statements, descriptions recalled: 1. Straight after presentation 2. After a 2 minute delay | — |
Secondary
| Measure | Time frame |
|---|---|
| Current secondary outcome measures as of 11/01/2017: All three studies: recognition scores and intrusion errors There was only one timepoint to this study, the research appointment lasted up to an hour and method was to simply count up the number of correct words/behaviours/statements recalled or recognised by each participant Previous secondary outcome measures: Recognition of words, statements and descriptions after recall tasks: 1. Straight after presentation 2. After a 2 minute delay | — |
Countries
England, United Kingdom
Outcome results
None listed