Primary Open Angle Glaucoma Eye Diseases
Conditions
Interventions
This study has two arms. Patients were randomized by selecting a prepackaged envelope with either the number 1 or 2 in it. Patients that select number 1 were assigned to group 1 and received 360 degr
Sponsors
University of Pikeville Kentucky College of Optometry
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1. Uncontrolled primary open angle glaucoma 2. Open angle on gonioscopy 3. Aged 25 to 90 years 4. Currently taking a prostaglandin analog, but IOP not controlled with monotherapy
Exclusion criteria
Exclusion criteria: 1. Best corrected visual acuity worse than 20/40 in the study eye (meaning 20/50 or worse) 2. Hx of angle closure or an occludable angle on gonioscopy 3. Untreated IOP less than or equal to 21 mmHg 4. Patients who have used a second IOP lowering medication in the past 2 months 5. Angle recession on gonioscopy 6. Pseudoexfoliation glaucoma 7. Pigment dispersion glaucoma 8. Prior incisional glaucoma surgery 9. Prior Microinvasive Glaucoma Surgery (MIGS, istent, Endocyclophotocoagulation) 10. Previous SLT or Argon Laser Trabeculoplasty (ALT) 11. Previous Laser Peripheral Iridotomy (LPI) 12. Previous refractive surgery 13. Inflammatory eye disease 14. Contraindication to any of the topical medicines including asthma, chronic obstruction pulmonary disease, bradycardia, or a hypersensitivity reaction. 15. A change in dosage, or addition of, a systemic medication that could effect IOP during the study 16. Women who are pregnant or who intend to become pregnant in the next 4 months (as verbally asked during the medical history and consenting process, no formal pregnancy test will be administered for this study) 17. Patients with significant dementia who are not able to fully comprehend the informed consent
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Intraocular pressure (IOP) at baseline and 8 weeks measured using Goldman tonometry. Baseline IOP was the average of two IOP measurements taken 30 minutes apart during the baseline exam. If the IOP measurements were greater than +/- 2 mmHg, a third IOP measurement was taken 30 minutes later. All follow up exams were within +/- 2 hour from the initial baseline exam to best control for diurnal fluctuations. Additionally, at each IOP measurement, two IOP readings will be taken and averaged. | — |
Secondary
| Measure | Time frame |
|---|---|
| 1. Ocular abnormality or inflammation identified using slit lamp examination of the cornea, anterior chamber, and lens at baseline and 8 weeks after the procedure. 2. Visual acuity assessed using a standard Snellen chart at baseline and 8 weeks | — |
Countries
United States of America
Outcome results
None listed