Major depressive disorder Mental and Behavioural Disorders
Conditions
Interventions
Participants enrolled in this study will be involved for a total duration of approximately 24 to 36 weeks, depending on whether they receive both the transcranial direct current stimulation (tDCS) and
Sponsors
Hospital District of Helsinki and Uusimaa
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1. Age 18–67 years 2. PHQ-9 score > 10 before treatment 3. Signed informed consent
Exclusion criteria
Exclusion criteria: 1. Safety risks, such as a concrete and imminent suicide plan, pregnancy or breastfeeding, magnetic metal parts in the upper body, or a significant risk of seizures. 2. Severe neurological conditions such as epilepsy or brain injury, as well as psychotic disorders 3. Impaired decision-making capacity 4. Those serving a prison sentence and those involved in forensic psychiatric proceedings
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Severity of depression measured using the self-evaluated Patient health questionnaire (PHQ-9) before and within 2 weeks after treatment | — |
Secondary
| Measure | Time frame |
|---|---|
| 1. Remission defined as PHQ-9 50 % less than MADRS before treatment 3. Severity of depression measured using the Montgomery Åsberg Depression Rating Scale (MADRS) rated before and within 2 weeks after treatment | — |
Countries
Finland
Contacts
Public ContactTuukka Raij
Outcome results
None listed