A novel minimally invasive surgical procedure for the treatment of femoral diaphyseal nonunions

Clinical outcome of a modified autologous BM transplantation vs. previously reported BM transplantation for the treatment of femoral diaphyseal nonunions

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

ISRCTN

Registry ID

ISRCTN29808592

Enrollment

Registered

2017-09-12

Start date

2009-01-01

Completion date

Unknown

Last updated

2020-12-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Femoral diaphyseal nonunions Musculoskeletal Diseases Femoral diaphyseal nonunions

Interventions

This study is a prospective single-group interventional study. All the participants in this study are allocated to the treatment group. All participants undergo the surgery of combined multidirectiona

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: 1. Presenting with atrophic nonunion of femoral diaphysis 2. Adults aged 18 or over

Exclusion criteria

Exclusion criteria: 1. Participant with local angular deformity 2. Participant with extremity shortening 3. Participant with internal fixation failure 4. Participant with mental comorbidity

Design outcomes

Primary

Measure	Time frame
1. Healing condition of cortices is measured using the Radiographic Union Scale for Tibial fractures (RUST) every month after operation 2. Bony union time is recorded when radiographic union is achieved, which was diagnosed by a RUST score = 10	—

Secondary

Measure	Time frame
1. Postoperative complications is collected from medical records at discharge from hospital 2. Health Economic assessment is assessed using length of hospital stay and serious adverse events including death within 90 days of surgery	—

Countries

China

Contacts

Public ContactYutong Meng

Outcome results

None listed

Source: ISRCTN (via WHO ICTRP) · Data processed: Feb 20, 2026