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Evaluation of an easy and pragmatic intervention to reduce antibiotic use for symptomatic respiratory infections in China

Evaluation of a tailored message package for educating patients to reduce antibiotics use for symptomatic respiratory-tract infections

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
ISRCTN
Registry ID
ISRCTN29801086
Enrollment
833
Registered
2022-09-23
Start date
2023-12-01
Completion date
Unknown
Last updated
2023-10-16

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Symptomatic respiratory tract infectious Respiratory

Interventions

A total of 30 township/community health centers within 2 cities, Anhui Province, China will be recruited. All the township/community health centers will be randomised at a 1:1 ratio to the control arm
while eligible patients in the intervention arm, will be sent 12 tailored massages in 12 consecutive days (once a day). Project evaluation applies to all arms using the same data collection methods an

Sponsors

National Natural Science Foundation of China
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: 1. 18 years or older and able to give consent to participate in the patient survey and/or follow-up interviews 2. Diagnosed with an RTIs in the recruitment consultation: blocked/runny nose, coughing with or without sputum, dry/sore throat, breathing problems, fever, ear inflammation (blocked ear, tinnitus, ear discharges, earache) 3. Able to read messages 4. Have a mobile phone that can receive messages

Exclusion criteria

Exclusion criteria: 1. Have previously sought treatment for this illness from a normal clinic 2. Unable to provide fully informed consent (e.g. due to dementia, psychosis, or severe depression) 3. Can't receive messages 4. Unable to read messages

Design outcomes

Primary

MeasureTime frame
Number of days in which antibiotics are used by patients with symptomatic RTIs measured using telephone questionnaire at initial consultation, 7 and 14 days

Secondary

MeasureTime frame
1. Patients’ knowledge about and attitude toward antibiotics measured using telephone questionnaire at 180 and 365 days 2. Patients’ quality of life measured using EQ-5D at initial consultation 7, 180 and 365 days 3. Patients' symptom severity and duration measured using telephone questionnaire at initial consultation, 7, 14 and 21 days 4. Times of re-visits to clinics and antibiotics re-prescription for the same RTI episode measured using telephone questionnaire at 14 and 21 days 5. Times of re-occurrence of RTIs within six or twelve months after the intervention and related health service seeking and antibiotics consumption measured using telephone questionnaire at 180 and 365 days

Countries

China

Outcome results

None listed

Source: ISRCTN (via WHO ICTRP) · Data processed: Feb 10, 2026