Chronic periodontitis Oral Health Chronic periodontitis
Conditions
Interventions
At baseline, all patients were treated with full mouth scaling and root planning. Periodontal pockets were divided into four groups. One of which is the control group, while group two received plain C
Sponsors
University of Malaya (Malaysia)
Eligibility
Sex/Gender
Male
Inclusion criteria
Inclusion criteria: 1. Twelve chronic periodontitis male aged between 35 and 56 years (mean age 41.8 ± 5.6) 2. Has at least 4 non adjacent teeth with periodontal pocket measuring =5mm
Exclusion criteria
Exclusion criteria: 1. History of systemic disease that might impact the course of periodontal disease or would require prophylactic antibiotics before dental treatment 2. Antibiotics or any modality of periodontal treatment in the past 3 months 3. Presence of overhanging restorations 4. Pregnancy, smoking habits, allergy to Selvadora Persica (Miswak)
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Current primary outcome measures as of 03/05/2013: In the current study the gel diffusion, Minimum Inhibitory Concentration (MIC) Minimum Bactericidal Concentration (MBC) tests and assessment of Bacteria Morphology with Scanning Electron Microscope (SEM) were used to evaluate the antibacterial effect of Salvadora persica extract and BITC chips on dental biofilm bacteria, results showed that both were able to inhibit bacteria growth and produced obvious alterations to the bacterial morphology. The result showed reductions in Probing Pocket Depth (PPD) in all 4 groups and these reductions are statistically significant in all 4 groups (p=0.01). The effects of the treatments were evident post treatment recording. At 2 months, PPD was reduced to 4.52 mm in the SRP alone group, to 5.27 in SRP plus chitosan, to 5.60 mm in the SRP plus Salvadora Persica chip group and to 4.63 mm in the SRP plus BITC chip group contrasted with pre-treatment records. Previous primary outcome measures until 03/05/2013: The result showed reductions in Probing Pocket Depth (PPD) in all 4 groups and these reductions are statistically significant in all 4 groups (p=0.01). The effects of the treatments were evident post treatment recording. At 2 months, PPD was reduced to 4.52 mm in the SRP alone group, to 5.27 in SRP plus chitosan, to 5.60 mm in the SRP plus Salvadora Persica chip group and to 4.63 mm in the SRP plus BITC chip group contrasted with pre-treatment records. | — |
Secondary
| Measure | Time frame |
|---|---|
| For bleeding on probing, the outcome shows that there was significant improvement in bleeding on probing in all groups post treatment. The enhancements in BOP were comparatively similar for all groups following 2 months (p=0.05). | — |
Countries
Malaysia
Outcome results
None listed