Assessment of the remineralizing effect of a toothpaste promoting the formation of tooth minerals

Qualitative and quantitative assessment of remineralizing effect of prophylactic toothpaste promoting brushite formation: a randomized clinical trial

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

ISRCTN

Registry ID

ISRCTN29509071

Enrollment

Registered

2020-01-27

Start date

2019-03-10

Completion date

Unknown

Last updated

2021-09-20

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Enamel hypersensitivity Oral Health

Interventions

Participants were randomly assigned to one of the study groups: Group 1 - used toothpaste promoting the formation of brushite (test group) Group 2 - used toothpaste wit

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: 1. Age 20 - 25 years 2. Enamel hypersensitivity

Exclusion criteria

Exclusion criteria: 1. Orthodontic appliance 2. Malocclusion 3. Allergic reactions to the components of toothpastes 4. Systemic diseases 5. Pregnancy

Design outcomes

Primary

Measure	Time frame
Teeth hypersensitivity measured with Shiff index daily for 5 - 6 days	—

Secondary

Measure	Time frame
1. Enamel acid resistance measured using the acid staining test daily for 5 - 6 days 2. Speed of remineralization measured as the number of days until tooth recovery using the above tests	—

Countries

Russian Federation

Outcome results

None listed

Source: ISRCTN (via WHO ICTRP) · Data processed: Feb 4, 2026