Comparative efficacy of albendazole and mebendazole against hookworm infection in Laos

Comparative efficacy of Albendazole and Mebendazole against hookworm infection: Randomised, controlled trial in schoolchildren in Khamkeuth district, Bolikhamxay province, Laos

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

ISRCTN

Registry ID

ISRCTN29126001

Enrollment

190

Registered

2008-10-09

Start date

2008-04-28

Completion date

Unknown

Last updated

2015-01-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Hookworm infection, and other intestinal helminth infections Infections and Infestations Hookworm diseases

Interventions

Mebendazole (500 mg, single dose, oral) vs albendzole (400 mg, single dose, oral) treatment.

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: 1. School-child age between 6 and 16 years, both male and female 2. Hookworm infected (at least one of four egg-positive Kato-Katz slide, established on 2 stool samples)

Exclusion criteria

Exclusion criteria: 1. Pregnancy 2. Severe illness 3. Non-consent

Design outcomes

Primary

Measure	Time frame
Hookworm parasite clearance (no hookworm egg in four Kato-Katz slides taken on two stool samples) at 21-23 days after treatment	—

Secondary

Measure	Time frame
Reduction of intensity of infection (reduction of mean number of hookworm eggs counted on four Kato-Katz slides taken on two different stool samples) at 21-23 days after treatment	—

Countries

Laos

Outcome results

None listed

Source: ISRCTN (via WHO ICTRP) · Data processed: Mar 27, 2026