Muskuloskeletal, total knee arthroplasty, analgesia Musculoskeletal Diseases Knee Arthroplasty
Conditions
Interventions
Femoral nerve block using 30ml of Levobupivicaine 0.25% versus Peri-articular infiltration of multimodal agents consisting of 150mg of Levobupivacaine, 10mg Morphine and 30mg Ketorolac diluted in 0.9%
Sponsors
University of Warwick (UK)
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: All patients undergoing an elective primary unilateral total knee replacement (TKA) under the care of an orthopaedic consultant at University Hospitals Coventry and Warwickshire NHS Trust
Exclusion criteria
Exclusion criteria: 1. Cognitive impairment, unable to complete questionnaire 2. Patients who lack capacity under the Mental Capacity Act 2005 3. Patients with pre-operative history of neruological abnormality in the ipsilateral leg e.g. history of stroke, neurogenic pain or previous nerve injury 4. Patients having spinal aneasthesia 5. Patients with specific contraindication to the analgesic agents used: Morphine, Ketorolac, Levobupivicaine
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Visual Analogue Scale at 18 hours post operation | — |
Secondary
| Measure | Time frame |
|---|---|
| Serum Levobupivacaine levels pre & post retransfusion 1. Functional assessment: 1.1. Straight leg raise 1.2. Mobility assessed bed to chair 18 & 48 hours post operatively 2. Oxford Knee Score 6 weeks post operatively | — |
Countries
United Kingdom
Outcome results
None listed