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How well certain signs in the body (biomarkers) can help doctors figure out if someone has a condition where blood flow to their abdomen is not working properly (abdominal ischemia).

Predictive value of biomarkers for the assessment of intestinal ischemia

Status
Recruiting
Phases
Unknown
Study type
Observational
Source
ISRCTN
Registry ID
ISRCTN29102136
Enrollment
50
Registered
2023-06-23
Start date
2022-12-20
Completion date
Unknown
Last updated
2023-07-04

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Early prediction and diagnosis of acute mesenteric ischemia Digestive System

Interventions

The prospectively planned study will include patients in whom acute mesenteric ischemia will be demonstrated by clinical presentation, radiological methods (ultrasound, CT - computed tomography, CTA -
*Anthropometric factors, *Associated diseases, *Drug treatment, *Bioimpedance measurements, *Differential blood status, LDH, AST, ALT, F

Sponsors

Ljubljana University Medical Centre
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: 1. Age: Over 18 years 2. Consent to take part

Exclusion criteria

Exclusion criteria: 1. Oncological disorders 2. Immunological disorders 3. Hematological disorders

Design outcomes

Primary

MeasureTime frame
Measured by blood sample at baseline and 24 hours: Differential blood status, LDH, AST, ALT, Fibrinogen, activated partial thromboplastin time, INR, CRP, PCT, D-dimer, I-FABP, D-Lactate, IL-6, Citrulline, DAO, GLP-1, VEGF, HIF1A

Secondary

MeasureTime frame
Measured using patient records at single time point: 1. Body weight (kg), Height (cm), BMI (kg/m²) 2. Symptom and medication history 3. Pain intensity (VAS 0 - 10) and duration 4. Findings from CT angiography of abdomen and pelvis 5. Surgical treatment, complications, follow up surgery 6. Lenght of stay (days)

Countries

Slovenia

Outcome results

None listed

Source: ISRCTN (via WHO ICTRP) · Data processed: Feb 4, 2026