Transcranial direct current stimulation (tDCS) combined with robotic rehabilitation for upper limbs in stroke

Randomized clinical trial of tDCS combined with robotic rehabilitation for upper limbs in stroke

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

ISRCTN

Registry ID

ISRCTN29077878

Enrollment

Registered

2022-03-22

Start date

2022-03-28

Completion date

Unknown

Last updated

2024-09-16

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Motor injuries of the upper limb and functional dependence in adults with stroke Nervous System Diseases

Interventions

Rehabilitation programs using robotic treatment combined with tDCS. The robot device is Amadeo, Tyromotion. The assignment to each of the groups was parallel. Participants were randomly assigned to th

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: 1. Age between 18 and 85 years old 2. Diagnosed stroke 3. Difficulties motor skills of the upper limb 4. Dependence in daily life activities 5. No other disabling pathology prior to the injury 6. Acceptance and signature of the informed consent

Exclusion criteria

Exclusion criteria: 1. Cognitive impairment (<24 in Mini-mental state exam) 2. Severe Aphasia 3. Upper limb fractures 4. Unresolved vascular problem 5. tDCS contraindications such as epilepsy 6. No signing informed consent

Design outcomes

Primary

Measure	Time frame
1. The impact of stroke on daily life was measured using the Functional Independence Measure at baseline, at the end of the study (20 sessions), and at 3 months. 2. Body functions (International Coaching Federation domains) were measured using the Fugl Meyer Motor Assessment at the end of the study (20 sessions) and at 3 months. 3. Activities (International Coaching Federation domains) were measured using ARA-T at the end of the study (20 sessions) and at 3 months. 4. Perceived quality of life was measured using the EuroQool-5 L test at baseline, at the end of the study (20 sessions), and at 3 months. 5. Satisfaction with the robot device and treatment was measured using the USEQ at baseline, at the end of the study (20 sessions), and at 3 months.	—

Measure

Time frame

1. The impact of stroke on daily life was measured using the Functional Independence Measure at baseline, at the end of the study (20 sessions), and at 3 months. 2. Body functions (International Coaching Federation domains) were measured using the Fugl Meyer Motor Assessment at the end of the study (20 sessions) and at 3 months. 3. Activities (International Coaching Federation domains) were measured using ARA-T at the end of the study (20 sessions) and at 3 months. 4. Perceived quality of life was measured using the EuroQool-5 L test at baseline, at the end of the study (20 sessions), and at 3 months. 5. Satisfaction with the robot device and treatment was measured using the USEQ at baseline, at the end of the study (20 sessions), and at 3 months.

—

Secondary

Measure	Time frame
1. Muscle tone assessment using modified Ashworth Test at baseline, the end of study (20 sessions), and 3 months. 2. Hand strength measured using dynamometer (using robot device) at baseline, the end of study (20 sessions), and 3 months. 3. Range of Motion (ROM) measured using goniometry (using robot device) at baseline, the end of study (20 sessions), and 3 months.	—

Countries

Spain

Outcome results

None listed

Source: ISRCTN (via WHO ICTRP) · Data processed: Feb 4, 2026