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Understanding the factors that affect clinical outcomes (such as tooth survival and apical healing) following non-surgical or surgical root canal treatment

A prospective evaluation of the individual and interactive influence of pre-operative, intra-operative and post-operative factors on the outcome of endodontic treatment procedures

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
ISRCTN
Registry ID
ISRCTN28863406
Enrollment
112
Registered
2018-06-28
Start date
1996-04-01
Completion date
Unknown
Last updated
2018-07-16

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Advanced periodontal disease Oral Health Periodontal disease

Interventions

The participants attend routine root canal treatment appointments and subsequent routine annual follow-ups for 4 years post-operatively. They only consent for donation of routine clinical data for the

Sponsors

Eastman Dental Institute, University College London
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: 1. With teeth that exhibited 5 mm or more clinical attachment loss or furcation involvement 2. With teeth that had undergone non-surgical periodontal debridement 3. Had undergone elective non-surgical root canal treatment prior to root amputation, or root canal treatment for management of concomitant pulpal or periapical pathosis followed by surgical periodontal debridement after being diagnosed as a “perio-endo” problem

Exclusion criteria

Exclusion criteria: 1. With teeth with incomplete periodontal or root canal treatment data 2. With teeth with incomplete root canal treatment

Design outcomes

Primary

MeasureTime frame
Tooth survival assessed using tooth extraction information provided by patients, referring dentists or notes in patients’ records. The duration of follow-up was annually up to 4 years post-treatment.

Secondary

MeasureTime frame
Periapical healing assessed using pain or swelling indicating periapical health based on clinical and radiographic examination. The duration of follow-up was annually up to 4 years post-treatment.

Countries

United Kingdom

Outcome results

None listed

Source: ISRCTN (via WHO ICTRP) · Data processed: Feb 4, 2026