Oral supplement in older adults to support physical fitness and mental well-being

Oral supplement Q-actin in older adults to support physical fitness and mental well-being

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

ISRCTN

Registry ID

ISRCTN28705061

Enrollment

Registered

2023-04-21

Start date

2022-12-12

Completion date

Unknown

Last updated

2025-09-08

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Osteoarthritis Musculoskeletal Diseases Arthrosis, unspecified

Interventions

Cucumbers have been anecdotally claimed to have anti-inflammatory activity for a long time, but the active principle was not identified. idoBR1 is an iminosugar amino acid isolated from fruits of cert

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: 1. Aged over 50 years 2. Consent 3. Commit to urine sampling 4. Able to commit to attending WARU or the remote centre for measurements of physical strength, finger dexterity, quality of life, diet choices, and sleep 5. Able to restrict from consumption of cucumber, gherkins, and melon for 2 days before coming to WARU or the remote centre

Exclusion criteria

Exclusion criteria: 1. Showing (or anyone within the household) any COVID-19 symptoms (see COVID-19 basic health screen)* 2. Higher risk or vulnerable to coronavirus or live with someone at a higher risk of a severe illness from COVID-19 (aged over 70 years, undergoing cancer treatment, high risk of getting infections) 3. Had a letter from the NHS advising you to shield (isolate) 4. Had been at risk of exposure to COVID-19 such as travel, contact with someone with COVID-19, being exposed to the virus, or has been asked to self-isolate by the track and trace system 5. Serious health conditions that require daily long-term medication

Design outcomes

Primary

Measure	Time frame
Physical strength measured using hand grip strength at 0, 6, and 12 weeks	—

Secondary

Measure	Time frame
1. Finger dexterity measured using Nine-Hole Peg Test (9HPT) at 0, 6, and 12 weeks 2. Generic quality of life measured using EQ-5D questionnaire at 0, 6, and 12 weeks 3. Diet choices measured using the Prime Diet Quality Score (PDQS) at 0, 6, and 12 weeks 4. Sleeping habits measured using the Pittsburgh Sleep Quality Index at 0, 6, and 12 weeks 5. Non-targeted metabolomics of urine samples at 0, 6 and 12 weeks Added 24/04/2023: 6. Knee and hip osteoarthritis assessed using the Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC) questionnaire at 0, 6, and 12 weeks	—

Measure

Time frame

1. Finger dexterity measured using Nine-Hole Peg Test (9HPT) at 0, 6, and 12 weeks 2. Generic quality of life measured using EQ-5D questionnaire at 0, 6, and 12 weeks 3. Diet choices measured using the Prime Diet Quality Score (PDQS) at 0, 6, and 12 weeks 4. Sleeping habits measured using the Pittsburgh Sleep Quality Index at 0, 6, and 12 weeks 5. Non-targeted metabolomics of urine samples at 0, 6 and 12 weeks Added 24/04/2023: 6. Knee and hip osteoarthritis assessed using the Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC) questionnaire at 0, 6, and 12 weeks

—

Countries

United Kingdom, Wales

Outcome results

None listed

Source: ISRCTN (via WHO ICTRP) · Data processed: Feb 4, 2026