HIV infection Infections and Infestations Human immunodeficiency virus [HIV] disease
Conditions
Interventions
Data on complaints (like otorrhea, ear pain, difficulty in hearing, tinnitus, difficulty in word discrimination, and feeling of fullness in the ear), type and duration of antiretroviral therapy, viral
Sponsors
FAPEMA
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1. Children living with HIV aged 18 months to 11 years 2. Attending the Hospital of the Federal University of Maranhão, in Northeast Brazil
Exclusion criteria
Exclusion criteria: 1. Family history of deafness 2. Consanguineous parents 3. Psychomotor developmental delay due to neurological disease 4. Craniofacial anomalies 5. Prematurity 6. Hospitalization to a neonatal intensive care unit 7. Meningitis 8. Treatment with chemotherapy 9. Perinatal co-infection (toxoplasmosis, rubella, cytomegalovirus, syphilis, herpes, HTLV-1, or viral hepatitis B and C), acute infection (external or middle ear) 10. Child uncooperative or aggressive
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Assessed at a single timpepoint: 1. Otologic complaints (like otorrhea, ear pain, difficulty in hearing, tinnitus, difficulty in word discrimination, and feeling of fullness in the ear) assessed using caregiver interview 2. Ear anatomy assessed using otoscopy 3. Hearing assessed using transient evoked otoacoustic emission (TEOAE) testing | — |
Secondary
| Measure | Time frame |
|---|---|
| Assessed at a single timpepoint: 1. Viral load, assessed using caregiver interview (the last test performed) 2. CD4+ cell count, assessed using caregiver interview (the last test performed) 3. Details of anti-retroviral therapy, assessed using caregiver interview | — |
Countries
Brazil
Outcome results
None listed