Chronic kidney disease, stages 3B-5 Urological and Genital Diseases
Conditions
Interventions
All patients with CKD Stage 3–5, referred to city nephrology center, are offered dietary counseling by experienced nephrologist. LPD is routinely recommended to all patients at high risk for CKD progr
Sponsors
St-Petersburg City Nephrology center
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1. Confirmed moderate GFR decline rate 2. Patient`s compliance to diet and pharmacological therapy 3. Prolonged history of regular EAA/KAA therapy according to the data from special database, recording patient’s` visits to drugstore for EAA/KAA supplied by budgetary funded source (= 10 consecutive visits with pre-defined for each CKD stage frequency).
Exclusion criteria
Exclusion criteria: 1. Patients with very low life expectancy 2. Patients with rapid CKD progression (more than 10 ml/min/1.73m2 per year)
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The change in eGFR decline scope (evaluated during two periods of five consequtive outpatient visit during the LPD (<0.6 g/kg/day) supplemented with EAA/KAA compared with that for patients with LPD (0.6-0.8 g/kg/day). The eGFR decline scope is calculated for every patient for both periods as a regression coefficient in 5 pairs: eGFR - visit date (ml/min/ per year). The frequency of the visits is predetermined according CKD stage: quarterly for CKD3, bimonthly for CKD4 and monthly for CKD5. | — |
Secondary
| Measure | Time frame |
|---|---|
| Change in quality of life parameters (evaluated by KDQoL questionnaire) | — |
Countries
Russian Federation
Contacts
Public ContactAlexander Zemchenkov
Outcome results
None listed