The effectiveness of E-health rehabilitation for patients with knee osteoarthritis

Effectiveness of telerehabilitation-based resistance exercise using a smartphone application in improving muscle strength, pain, physical performance, and adherence among patients with knee osteoarthritis: a randomized controlled trial

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

ISRCTN

Registry ID

ISRCTN28185135

Enrollment

Registered

2025-11-04

Start date

2025-11-15

Completion date

Unknown

Last updated

2026-04-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Knee osteoarthritis (KOA) Musculoskeletal Diseases

Interventions

Participants eligible for the study will be randomly assigned in a 1:1 ratio to either the intervention group (app-based home exercise program) or the control group (paper-based home exercise program)

Eligibility

Sex/Gender

All

Age

40 Years to 70 Years

Inclusion criteria

Inclusion criteria: 1. Adults aged 40–70 years 2. Diagnosed with mild-to-moderate KOA 3. Able to use a smartphone 4. Able to perform resistance exercises independently

Exclusion criteria

Exclusion criteria: 1. Severe KOA or knee surgery in the past 6 months 2. Neurological or musculoskeletal disorders affecting lower limbs 3. Cognitive impairment or inability to follow instructions

Design outcomes

Primary

Measure	Time frame
1. Pain is measured using the Arabic Numeric Pain Rating Scale (ANPRS) at baseline and 6 weeks post-intervention 2. Osteoarthritis symptoms, including pain, stiffness, and physical function, are measured using the Arabic version of the WOMAC at baseline and 6 weeks post-intervention 3. Quadriceps muscle strength is measured using a hand-held dynamometer (HHD, microFET®2) at baseline and 6 weeks post-intervention	—

Measure

Time frame

1. Pain is measured using the Arabic Numeric Pain Rating Scale (ANPRS) at baseline and 6 weeks post-intervention 2. Osteoarthritis symptoms, including pain, stiffness, and physical function, are measured using the Arabic version of the WOMAC at baseline and 6 weeks post-intervention 3. Quadriceps muscle strength is measured using a hand-held dynamometer (HHD, microFET®2) at baseline and 6 weeks post-intervention

—

Secondary

Measure	Time frame
1. Exercise adherence is measured using a self-reported exercise logbook, with adherence ratio calculated weekly over 6 weeks 2. Exercise self-efficacy is measured using the Arabic Exercise Self-Efficacy Scale (ESES-A) at baseline and 6 weeks post-intervention 3. Lower-limb functional strength is measured using the 30-Second Chair Stand Test (30 CST) and Five-Times Sit-to-Stand Test (FTSST) at baseline and 6 weeks post-intervention 4. Dynamic balance and mobility are measured using the Timed-Up and Go (TUG) test at baseline and 6 weeks post-intervention	—

Measure

Time frame

1. Exercise adherence is measured using a self-reported exercise logbook, with adherence ratio calculated weekly over 6 weeks 2. Exercise self-efficacy is measured using the Arabic Exercise Self-Efficacy Scale (ESES-A) at baseline and 6 weeks post-intervention 3. Lower-limb functional strength is measured using the 30-Second Chair Stand Test (30 CST) and Five-Times Sit-to-Stand Test (FTSST) at baseline and 6 weeks post-intervention 4. Dynamic balance and mobility are measured using the Timed-Up and Go (TUG) test at baseline and 6 weeks post-intervention

—

Countries

Saudi Arabia

Contacts

Public ContactShuruq Azhar

Shuruqazhar@gmail.com-

Outcome results

None listed

Source: ISRCTN (via WHO ICTRP) · Data processed: May 1, 2026