A randomised trial to establish the effectiveness of graduated compression stockings (GCS) to prevent post stroke deep venous thrombosis and pulmonary embolism (PE)

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

ISRCTN

Registry ID

ISRCTN28163533

Enrollment

5500

Registered

2003-08-11

Start date

2003-10-01

Completion date

Unknown

Last updated

2015-01-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Cardiovascular/Stroke Circulatory System Deep vein thrombosis

Interventions

Trial 1: Full length GCS and routine care Or Routine care and avoid GCS Trial 2: Full length GCS and routine care Or Below knee GCS and routine care

Eligibility

Inclusion criteria

Inclusion criteria: Immobile patients with an acute stroke, in whom the responsible clinician/nurse is uncertain about either the value of graduated compression stockings (GCS) or the optimal length

Exclusion criteria

Exclusion criteria: 1. Patients who, in the opinion of the responsible clinician/nurse, are unlikely to benefit from graduated compression stockings 2. Patients with subarachnoid haemorrhage 3. Patients with peripheral vascular disease, diabetic or sensory neuropathy, where the responsible clinician/nurse judges that stockings may cause tissue necrosis

Design outcomes

Primary

Measure	Time frame
Presence of first symptomatic or asymptomatic DVT in the popliteal or femoral veins detected on either of two routine Doppler ultrasound scans (performed at about 7-10 days and 25-30 days) or contrast venography within 30 days of randomisation	—

Secondary

Measure	Time frame
Not provided at time of registration	—

Countries

Australia, Italy, United Kingdom

Outcome results

None listed

Source: ISRCTN (via WHO ICTRP) · Data processed: Apr 3, 2026