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Oxytocin dose effects during cesarean section

Oxytocin dose effects on ST segment changes, arterial hypotension and blood loss volume in parturients of different ages during cesarean section

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ISRCTN
Registry ID
ISRCTN28030442
Enrollment
45
Registered
2019-10-03
Start date
2016-10-01
Completion date
Unknown
Last updated
2019-10-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Control of bleeding during cesarean section Pregnancy and Childbirth Cesarean section

Interventions

All patients were randomized into 2 arms according to OT dosing given by various clinical guidelines: 5 IU and 10 IU. The rate of intravenous drip of oxytocin in all puerperas was equal to 0.5 IU/mi

Sponsors

Federal state budget educational institution higher education «Amur State Medical Academy» of the Ministry of Health of the Russian Federation.
Lead Sponsor

Eligibility

Sex/Gender
Female

Inclusion criteria

Inclusion criteria: 1. Full-term singleton pregnancy 2. Elective cesarean section 3. Age of 15 to 25 years inclusive 4. Body mass index (BMI) below 25 kg/m² 5. Pregnancy and labor parity - 1

Exclusion criteria

Exclusion criteria: 1. Severe extragenital diseases 2. Preeclampsia and eclampsia

Design outcomes

Primary

MeasureTime frame
1. Intraoperative ST segment depression measured using intraoperative ECG monitoring (II standard lead), ST segment depression (mm); ST segment status was analyzed using BeneView T6 patient monitor (Mindray, China). 2. Intraoperative hypotension: Arterial hypotension was noted as systolic blood pressure below 80 mm Hg, lasted less than 5 min. and was controlled with IV microfluidic infusion of noradrenalin solution with the rate of 0.03 µg/kg/min.

Secondary

MeasureTime frame
Intraoperative blood loss was determined using indirect visual method by a team of MD’s, which included: a surgeon (obstetrician-gynecologist, highest Qualification Grade), an assistant surgeon and an anesthesiologist-intensivist (highest Qualification Grade).

Countries

Russian Federation

Contacts

Public ContactEvgeny Degtyaryov
dormicumtrade@gmail.com+7 89246751015

Outcome results

None listed

Source: ISRCTN (via WHO ICTRP) · Data processed: Feb 4, 2026