An investigation of malnutrition, obesity, diabetes, high blood pressure and severe COVID-19 in Italy

Malnutrition, obesity, diabetes, hypertension and severe COVID-19 in Italy

Status

Recruiting

Phases

Unknown

Study type

Observational

Source

ISRCTN

Registry ID

ISRCTN27707558

Enrollment

2000

Registered

2020-12-30

Start date

2020-02-01

Completion date

Unknown

Last updated

2021-01-11

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

To investigate the association between obesity, diabetes, hypertension and malnutrition with severe COVID-19 outcome (SARS-CoV-2 infection) in hospital settings Infections and Infestations COVID-19 (SARS-CoV-2 infection)

Interventions

Patients must fulfil the inclusion criteria for entry. Data will be extracted from the medical records and databases of each center. In the case of patients who have previously given written consent t

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: 1. Hospitalized patients 2. Proven COVID-19 disease 3. Aged 18 and above

Exclusion criteria

Exclusion criteria: Does not meet inclusion criteria

Design outcomes

Primary

Measure	Time frame
Measured using patient records (and a telephone interview if required) at a single time point: 1. Demographics 1.1. Age 1.2. Ethnicity 1.3. Current or previous work activity 1.4. Self-sufficient patient (yes/no) 1.5. In a nursing home (yes/no) 1.6. Caregiver (yes/no) 2. Hospitalisation and outcome 2.1. Duration of hospitalization (days) 2.2. Transferred to resuscitation (yes/no) 2.3. Recovery (yes/no) 3. Vaccinated for influenza or pneumococcus (yes/no) 4. Anthropometric data 4.1. Height (cm) 4.2. Weight (kg) 4.3. Waist circumference (cm) 5. Medication history before admission 6. Hematology at entry and near discharge 6.1. Leukocytes (x10(9)/L) 6.2. Red blood cells (x10(12)/L) 6.3. Hemoglobin - HB (g/dl) 6.4. Hematocrit - Hct (%) 6.5. MCV (f/L) 6.6. Platelets (x10(9)/L) 6.7. Lymphocytes (x10(9)/L) 6.8. Neutrophils (x10(9)/L) 7. Lab values at entry and near discharge 7.1. Blood glucose (mg/dl) 7.2. HbA1c (%) 7.3. Creatinine (mg/ml) 7.4. Total cholesterol (mg/dl) 7.5. HDL cholesterol (mg/dl) 7.6. Triglycerides (mg/dl) 7.7. ALT (U/L) 7.8. AST (U/L) 7.9. GGT (U/L) 7.10. Albunemia (%) 7.11. Total proteins (g/dl) 7.12. eGFR IL-6 (pg/ml) 7.13. C-reactive protein (mg/dl) 7.14. CK (mg/dl) 7.15. LDH (U/L) 7.16. Ferritin (ng/ml) 8. Blood gas values at entry and near discharge	—

Measure

Time frame

Measured using patient records (and a telephone interview if required) at a single time point: 1. Demographics 1.1. Age 1.2. Ethnicity 1.3. Current or previous work activity 1.4. Self-sufficient patient (yes/no) 1.5. In a nursing home (yes/no) 1.6. Caregiver (yes/no) 2. Hospitalisation and outcome 2.1. Duration of hospitalization (days) 2.2. Transferred to resuscitation (yes/no) 2.3. Recovery (yes/no) 3. Vaccinated for influenza or pneumococcus (yes/no) 4. Anthropometric data 4.1. Height (cm) 4.2. Weight (kg) 4.3. Waist circumference (cm) 5. Medication history before admission 6. Hematology at entry and near discharge 6.1. Leukocytes (x10(9)/L) 6.2. Red blood cells (x10(12)/L) 6.3. Hemoglobin - HB (g/dl) 6.4. Hematocrit - Hct (%) 6.5. MCV (f/L) 6.6. Platelets (x10(9)/L) 6.7. Lymphocytes (x10(9)/L) 6.8. Neutrophils (x10(9)/L) 7. Lab values at entry and near discharge 7.1. Blood glucose (mg/dl) 7.2. HbA1c (%) 7.3. Creatinine (mg/ml) 7.4. Total cholesterol (mg/dl) 7.5. HDL cholesterol (mg/dl) 7.6. Triglycerides (mg/dl) 7.7. ALT (U/L) 7.8. AST (U/L) 7.9. GGT (U/L) 7.10. Albunemia (%) 7.11. Total proteins (g/dl) 7.12. eGFR IL-6 (pg/ml) 7.13. C-reactive protein (mg/dl) 7.14. CK (mg/dl) 7.15. LDH (U/L) 7.16. Ferritin (ng/ml) 8. Blood gas values at entry and near discharge

—

Secondary

Measure	Time frame
There are no secondary outcome measures	—

Countries

Italy

Outcome results

None listed

Source: ISRCTN (via WHO ICTRP) · Data processed: Feb 4, 2026