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The effect of probiotic and fluoride mouthwashes on dental plaque

The evaluation of the effectiveness of probiotic mouthwashes in reducing dental plaque in primary and permanent teeth: Randomized clinical trial

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ISRCTN
Registry ID
ISRCTN27684426
Enrollment
30
Registered
2022-08-09
Start date
2020-01-29
Completion date
Unknown
Last updated
2022-08-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Dental plaque Oral Health

Interventions

The present study is a randomized controlled trial including 30 healthy children (12 male, 18 female) from Dar Al-Rahma for orphan children in Damascus, Syrian Arab Republic assigned into two parallel

Sponsors

Damascus University
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: 1. Aged between 8-10 years old 2. Systemically healthy children with good oral health 3. Eruption of permanent incisor and first permanent molar 4. Presence of primary second molar, no decay on the buccal surface of examined teeth 5. Children who are able to cooperate with the study

Exclusion criteria

Exclusion criteria: 1. Children with physical, mental, or physical disabilities 2. Use of antibiotics, anti-inflammatories, or oral rinses at least four weeks before this study 3. Undergoing a preventive oral program during the past three months before the start of the tests 4. Sensitivity to one of the research materials

Design outcomes

Primary

MeasureTime frame
Plaque accumulation measured using the Turesky Modified Quigley – Hein (TMQH) plaque index on days 7, 14 and 30

Secondary

MeasureTime frame
There are no secondary outcome measures

Countries

Syria

Outcome results

None listed

Source: ISRCTN (via WHO ICTRP) · Data processed: Feb 4, 2026