Nutritional, Metabolic, Endocrine: Hyperthyroidism Nutritional, Metabolic, Endocrine Thyrotoxicosis [Hyperthyroidism]
Conditions
Interventions
All the patients identified as suitable for radioactive iodine treatment will be referred to the endocrine specialist nurse as per the routine practice. The patients will then be screened for the incl
Sponsors
Record Provided by the NHSTCT Register - 2006 Update - Department of Health
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1. Toxic nodular thyroid disease (toxic multinodular goitre or toxic nodule) 2. Garves' thyrotoxicosis with patients' preference to have RAI 3. Recurrent Graves' thyrotoxicosis 4. Age between 18 and 80 years. According to the current local practice, patients needing radioactive iodine treatment will be seen by our Endocrine Specialist Nurses. These patients will be assessed for their eligibility for this study. If the patients are eligible, they will be given the information sheet about the study. If they are happy to take part, before the radioactive iodine treatment, written consent will be obtained and patients will be randomised at that stage.
Exclusion criteria
Exclusion criteria: 1. Pregnant or lactating women 2. Patients allergic to antithyroid drugs or iodine 3. Active thyroid eye disease 4. Known alcohol or drug abuse 5. Significant psychiatric disturbances
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Differences in the scores on SF36-II & GHQ-12 between the 2 groups at 6 weeks, 6 months and 12 months, controlling for the baseline scores | — |
Secondary
| Measure | Time frame |
|---|---|
| Not provided at time of registration | — |
Countries
United Kingdom
Outcome results
None listed