Improvement of gingival thickness in patients with thin gingiva biotype who undergoing dental implantation Oral Health
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1. Aged 18-60 years 2. Patients with single or multiple non-restorable teeth 3. Thin biotype of gingiva 4. Sufficient bone of alveolar ridge 5. Absence of untreated periodontal disease
Exclusion criteria
Exclusion criteria: 1. Pregnancy 2. Systemic diseases 3. Thick biotype 4. Insufficient bone
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| 1. Width of the keratinized tissue determined by measuring the distance between the mucogingival junction (MGJ) and free gingiva using a graduated periodontal probe at baseline, 3 and 6 months after the surgical procedure 2. Thickness measured by the cone-beam computed tomography (CBCT) with Ez3D-1 software (Vatech, Korea) before and 3, 6 months after the surgical procedure. The measurement of the thickness of mucous for determination of biotype was provided according to the following steps: before the examination in the vestibule site of the oral cavity dental cotton swabs were put, measurements are carried out in the frontal and sagittal dimensions in areas corresponding to the vestibular cortical plates of the root of the examined tooth, in the projection of the central axis of the tooth, from the top of the cortical plate to the mucogingival junction. | — |
Secondary
| Measure | Time frame |
|---|---|
| 1. Wound healing (epithelialization) measured using a cytological analysis at baseline, 3, 5, 7, and 10 days 2. Local immunity measured using a sandwich enzyme-linked immunosorbent assay (ELISA) for determination of the concentration of pro- and anti-inflammatory cytokines (IL-1ß, TNFa and IL-4) in the peri-implant cervicular fluid at baseline, 1, 7 and 30 days 3. Gingival blood flow measured using a laser Doppler flowmetry (LDF) at baseline,1, 7 and 14 days 4. Esthetic result (mesial and distal papilla, soft tissue level, soft tissue contour, alveolar process deficiencies, soft tissue color, and texture) measured using a Pink esthetic score (PES) at 6 months after the prosthetic phase | — |
Countries
Kazakhstan