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Randomised controlled trial of manualised out-patient individual and group therapy for borderline personality disorder

Effectiveness of intensive out-patient psychotherapy for treatment of borderline personality disorder: a pragmatic randomised single blind controlled study

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ISRCTN
Registry ID
ISRCTN27660668
Enrollment
100
Registered
2008-10-21
Start date
2003-03-03
Completion date
Unknown
Last updated
2016-10-17

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Borderline personality disorder Mental and Behavioural Disorders Specific personality disorders

Interventions

Mentalisation based therapy (MBT) compared with structured clinical management (SCM): 1. MBT consists of mentalising focus work in an individual session and a group session once per week 2. SCM consis

Sponsors

Barnet, Enfield and Haringey Mental Health Trust (UK)
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: 1. Diagnosis of BPD2 2. Suicide attempt or episode of severe self-harm within last six months 3. Aged 18 - 65 years, either sex

Exclusion criteria

Exclusion criteria: 1. Currently in a long term psychotherapeutic treatment 2. Meet Diagnostic and Statistical Manual of Mental Disorders - Fourth Edition (DSM-IV) criteria for psychotic disorder or bipolar I disorder 3. Have opiate dependence with physiological dependence requiring specialist treatment 4. Have mental impairment or evidence of organic brain disorder

Design outcomes

Primary

MeasureTime frame
The presence or absence or frequency in a 6-month period of severe parasuicidal behaviour as indicated by: 1. Suicide attempt 2. Life-threatening self-harm 3. Hospital admission. Hospital is included because in general mental health services patients with BPD are primarily offered in-patient care in anticipation of suicide attempts and during episodes of severe self-harm.

Secondary

MeasureTime frame
1. Psychiatric symptoms 2. Social and interpersonal function Measured at baseline and at 6-monthly intervals to the end of treatment and then yearly over the follow-up period.

Countries

United Kingdom

Outcome results

None listed

Source: ISRCTN (via WHO ICTRP) · Data processed: Mar 12, 2026