Influence of geographic altitude on the evolution of severe cases of COVID-19 in Ecuador

Influence of geographic altitude on the evolution of COVID-19 patients admitted to the intensive care units (ICUs) in Ecuador

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

ISRCTN

Registry ID

ISRCTN27613785

Enrollment

817

Registered

2021-08-16

Start date

2021-02-12

Completion date

Unknown

Last updated

2021-08-30

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Severe cases of COVID-19 (SARS-CoV-2 infection) requiring ICU and mechanical ventilation Infections and Infestations

Interventions

Retrospective data collection from the cohort of patients diagnosed with severe COVID-19 between the months of March to July 2021, admitted to Intensive Care Units of hospitals located in Ecuadorian c

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: 1. Patients (men and women) 18 years old or older 2. Diagnosed with COVID-19 by RT-PCR 3. Admitted to ICUs in Ecuador located in cities with geographic altitude of 2500 ms above sea level and at sea level 4. Need for mechanical ventilation as part of their management

Exclusion criteria

Exclusion criteria: 1. Patients younger than 18 years of age 2. Patients admitted to ICU for a diagnosis other than COVID-19 and also required mechanical ventilation 3. Foreign patients

Design outcomes

Primary

Measure	Time frame
Mortality (%) of patients diagnosed with severe COVID-19 between the months of March to July 2021 measured from retrospectively collected hospital data at a single time point	—

Secondary

Measure	Time frame
1. Duration of mechanical ventilation (in days) of patients diagnosed with severe COVID-19 between the months of March to July 2021 measured from retrospectively collected hospital data at a single time point 2. Duration of ICU admission and duration hospitalization (in days) of patients diagnosed with severe COVID-19 between the months of March to July 2021 measured from retrospectively collected hospital data at a single time point 3. PaO2/FiO2 index of patients diagnosed with severe COVID-19 between the months of March to July 2021 measured from retrospectively collected hospital data at a single time point 2. Mortality risk factors of patients diagnosed with severe COVID-19 between the months of March to July 2021 measured from retrospectively collected hospital data at a single time point 3. Comorbidities of patients diagnosed with severe COVID-19 between the months of March to July 2021 measured from retrospectively collected hospital data at a single time point 4. Symptoms and signs prior to admission to the ICU of patients diagnosed with severe COVID-19 between the months of March to July 2021 measured from retrospectively collected hospital data at a single time point 5. Severity indexes of patients diagnosed with severe COVID-19 between the months of March to July 2021 measured from retrospectively collected hospital data at a single time point 6. Initial management of patients diagnosed with severe COVID-19 between the months of March to July 2021 measured from retrospectively collected hospital data at a single time point 7. Laboratory data of patients diagnosed with severe COVID-19 between the months of March to July 2021 measured from retrospectively collected hospital data at a single time point 8. Hemodynamic variables of patients diagnosed with severe COVID-19 between the months of March to July 2021 measure	—

Measure

Time frame

1. Duration of mechanical ventilation (in days) of patients diagnosed with severe COVID-19 between the months of March to July 2021 measured from retrospectively collected hospital data at a single time point 2. Duration of ICU admission and duration hospitalization (in days) of patients diagnosed with severe COVID-19 between the months of March to July 2021 measured from retrospectively collected hospital data at a single time point 3. PaO2/FiO2 index of patients diagnosed with severe COVID-19 between the months of March to July 2021 measured from retrospectively collected hospital data at a single time point 2. Mortality risk factors of patients diagnosed with severe COVID-19 between the months of March to July 2021 measured from retrospectively collected hospital data at a single time point 3. Comorbidities of patients diagnosed with severe COVID-19 between the months of March to July 2021 measured from retrospectively collected hospital data at a single time point 4. Symptoms and signs prior to admission to the ICU of patients diagnosed with severe COVID-19 between the months of March to July 2021 measured from retrospectively collected hospital data at a single time point 5. Severity indexes of patients diagnosed with severe COVID-19 between the months of March to July 2021 measured from retrospectively collected hospital data at a single time point 6. Initial management of patients diagnosed with severe COVID-19 between the months of March to July 2021 measured from retrospectively collected hospital data at a single time point 7. Laboratory data of patients diagnosed with severe COVID-19 between the months of March to July 2021 measured from retrospectively collected hospital data at a single time point 8. Hemodynamic variables of patients diagnosed with severe COVID-19 between the months of March to July 2021 measure

—

Countries

Ecuador

Contacts

Public ContactManuel Jibaja

edison.jibaja@hee.gob.ec+593 (0)999668588

Outcome results

None listed

Source: ISRCTN (via WHO ICTRP) · Data processed: Feb 4, 2026