The Finnish Rectal Cancer Study

A prospective randomized multicenter trial to compare the results of combined short-term preoperative radiotherapy, postoperative 5-FU based chemotherapy and total mesorectal excision with total mesorectal excision alone in the treatment of resectable rectal cancer

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

ISRCTN

Registry ID

ISRCTN27293422

Enrollment

280

Registered

2012-07-09

Start date

1995-01-01

Completion date

Unknown

Last updated

2017-05-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Rectal cancer Cancer Malignant neoplasm of rectum

Interventions

After informed consent had been received patients were randomized at the Finnish Cancer Registry. The randomization process was a true one, no blocks were used. The randomization was done between sur

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: 1. Aged 18 - 80 years 2. Clinical stage II-III primary rectal adenocarcinoma

Exclusion criteria

Exclusion criteria: 1. Obstructive tumours 2. Tumours invading adjacent organs 3. Patients with a diagnosis of another cancer less than five years previously, with ulcerative colitis 4. Crohn´s disease 5. Familial polyposis 6. Hereditary nonpolypotic colorectal carcinoma

Design outcomes

Primary

Measure	Time frame
1. 5 year survival 2. 5 year local recurrence rate	—

Secondary

Measure	Time frame
Postoperative complications	—

Countries

Finland

Outcome results

None listed

Source: ISRCTN (via WHO ICTRP) · Data processed: Feb 4, 2026