Cardiovascular disease Circulatory System Nicotine replacement therapy
Conditions
Interventions
Nicotine replacement therapy in the form of patches versus placebo
Sponsors
University of Oxford (UK)
Eligibility
Inclusion criteria
Inclusion criteria: All smokers (self-report =10 cigarettes per day) aged 18 years and over who wish to stop with (at least) one of the following diagnoses: 1. Ischaemic Heart Disease: i. Stable Angina, clinically or exercise electrocardiogram (ECG) diagnosed ii. Myocardial infarction more than 2 months previously with recovery uncomplicated by any rhythm disturbances other than atrial fibrillation 2. Cerebrovascular disease: No exclusions 3. Peripheral vascular disease: No exclusions
Exclusion criteria
Exclusion criteria: 1. Patients the GP, for whatever reason, does not wish to include 2. Known skin hypersensitivity to nicotine, plasters or widespread active eczema/psoriasis or other skin conditions that would restrict patch application 3. Pregnant or breast feeding women or those who are not using reliable contraceptive methods 4. Phaeochromocytoma/Hyperthyroidism and severe renal and/or hepatic impairment 5. Severe (life threatening) arrhythmia 6. Command of English (+/- interpreter) or impairment of faculties does not allow informed consent
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Not provided at time of registration. | — |
Secondary
| Measure | Time frame |
|---|---|
| Not provided at time of registration. | — |
Countries
United Kingdom
Outcome results
None listed