Effect of methylphenidate on neural mechanisms underlying attention deficit after closed head injury

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

ISRCTN

Registry ID

ISRCTN27103516

Enrollment

Registered

2003-09-12

Start date

2003-05-01

Completion date

Unknown

Last updated

2016-10-17

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Attention deficit after closed head injury Mental and Behavioural Disorders Intracranial injury

Interventions

Double-blind, placebo controlled, crossover design and open trials (pilot study). The study is aimed to evaluate the effectiveness of a neurophysiological method, Event-related brain potentials (ERPs

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: Closed head injured patients

Exclusion criteria

Exclusion criteria: 1. Current history of neurological and/or psychiatric disorders 2. History of movement disorders 3. Epilepsy 4. Current use of MAO inhibitors or coumarin anticoagulants 5. Drug abuse 6. Problems of galactose intolerance 7. The Lapp lactase deficiency or glusoce-galactose malabsorption 8. Severe hypertension 9. Cardiac arrhythmia 10. Angina pectoris 11. Hyperthyroidism 12. Glaucoma 13. Thyrotoxicosis 14. Pregnancy 15. Severe hand motor deficit

Design outcomes

Primary

Measure	Time frame
Not provided at time of registration	—

Secondary

Measure	Time frame
Not provided at time of registration	—

Countries

United Kingdom

Outcome results

None listed

Source: ISRCTN (via WHO ICTRP) · Data processed: Feb 4, 2026