Pregnancy-associated osteoporosis Pregnancy and Childbirth
Conditions
Interventions
Phase 1:
The first phase of the study involves the completion of an online survey that asks its respondents for information about the diagnosis of their PAO
treatments taken, mode of diagnosis, symptoms at presentation, quality of life etc.
Phase 2:
Participants can consent online to be contacted to take part in Phase 2 of the study. This involves havin
Sponsors
Accord (United Kingdom)
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: PAO cases: 1. Previously diagnosed with PAO 2. Willing and able to give informed consent Controls: 1. Women known to a PAO participant who had a baby around the same time as a participant who was not diagnosed with PAO 2. Willing and able to give informed consent
Exclusion criteria
Exclusion criteria: Does not meet the inclusion criteria
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Bone mineral density change in relation to treatment received (if any), measured using dual-energy x-ray absorptiometry (DEXA) at all timepoints available after the initial diagnosis for up to 5 years | — |
Secondary
| Measure | Time frame |
|---|---|
| 1. Quality of life measured using SF36 at diagnosis recorded retrospectively at the time of answering the survey 2. Participant reported fracture number and type at diagnosis recorded retrospectively at the time of answering the survey 3. Validated fractures recorded on the participant's medical record at the original diagnosis and following the original diagnosis for up to 5 years 4. Recurrence of fractures during subsequent pregnancies as recorded on the participant’s medical record at any timepoint | — |
Countries
England, Scotland, United Kingdom
Outcome results
None listed