Scar study

What is the pattern and interrelationship between the biomarkers of scarring and fibrosis and the observed phenotypic scarring severity

Status

Recruiting

Phases

Unknown

Study type

Observational

Source

ISRCTN

Registry ID

ISRCTN27023864

Enrollment

300

Registered

2016-10-20

Start date

2016-09-09

Completion date

Unknown

Last updated

2021-01-05

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Cutaneous scarring Skin and Connective Tissue Diseases Cutaneous scarring

Interventions

Potential participants will be approached by the research team after a consultant plastic surgeon has planned scar revision surgery. An information sheet and explanation about the study will be given

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: 1. Aged over 18 2. Patients with a scar suitable for surgical excision

Exclusion criteria

Exclusion criteria: Not meeting exclusion criteria

Design outcomes

Primary

Measure	Time frame
Scar severity is measured using modified Vancouver scar scale, Patient and Observer scar scale and the Manchester scar scale before surgery.	—

Secondary

Measure	Time frame
Expression of Biomarker level in scar sample biopsy is measured using semi quantitative immune-histochemistry and gross morphology of skin section using histological stains at the time of surgery.	—

Countries

United Kingdom

Contacts

Public ContactSimon Booth

simon.booth@nhs.net+44 (0)1342 414000

Outcome results

None listed

Source: ISRCTN (via WHO ICTRP) · Data processed: Feb 4, 2026