Effect of exercise training on fat distribution in patients with type 2 diabetes

Effect of exercise training on ectopic fat accumulation in patients with type 2 diabetes

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

ISRCTN

Registry ID

ISRCTN26977705

Enrollment

Registered

2011-04-08

Start date

2010-02-24

Completion date

Unknown

Last updated

2015-01-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Type 2 diabetes mellitus Nutritional, Metabolic, Endocrine Non-insulin-dependent diabetes mellitus

Interventions

Patients are studied before and after a six month exercise intervention

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: 1. Ages of 18 - 70 years 2. Diagnosis of type 2 diabetes mellitus

Exclusion criteria

Exclusion criteria: 1. Complications of diabetes (retinopathy, neuropathy, nephropathy) 2. Hypertension (systolic blood pressure > 165 mmHg and/or diastolic blood pressure > 95 mmHg) 3. Body mass index (BMI) > 35kg/m2 4. Smoking 5. Cardiac diseases 6. Claustrophobia or any other contra-indication for magnetic resonance imaging (MRI)

Design outcomes

Primary

Measure	Time frame
1. Visceral and subcutaneous abdominal fat volume 2. Myocardial, myocellular and hepatic triglyceride content 3. Epi- and pericardal fat volume	—

Secondary

Measure	Time frame
1. Cardiac function 2. Anthropometric measures (weight, blood pressure) 3. Energy intake and expenditure 4. Metabolic parameters (HbA1c, lipid levels from blood plasma)	—

Countries

Netherlands

Outcome results

None listed

Source: ISRCTN (via WHO ICTRP) · Data processed: Feb 4, 2026