Transatlantic registry of type A aortic dissection

Transatlantic registry of Type A aortic dissection

Status

Recruiting

Phases

Unknown

Study type

Observational

Source

ISRCTN

Registry ID

ISRCTN26697221

Enrollment

10000

Registered

2025-12-29

Start date

2025-05-16

Completion date

Unknown

Last updated

2026-01-12

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Type A aortic dissection Circulatory System

Interventions

Patients included in this registry are those who underwent surgery for type A aortic dissection. Surgical repair of this severe condition is the only treatment available to prevent aortic rupture. Sur

Eligibility

Sex/Gender

All

Age

18 Years to 100 Years

Inclusion criteria

Inclusion criteria: 1. Type A aortic dissection or intramural hematoma involving the aortic root/ascending aorta 2. Patients aged > 18 years 3. Symptoms started within 7 days before surgery 4. Primary surgical repair of acute TAAD 5. Any other major cardiac surgical procedure concomitant with surgery for TAAD

Exclusion criteria

Exclusion criteria: 1. Patients aged 7 days from surgery 3. Prior procedure for TAAD 4. Type non-A non-B aortic dissection 5. Retrograde TAAD (with primary tear located in descending aorta) 6 Concomitant endocarditis 7. TAAD secondary to blunt or penetrating chest trauma

Design outcomes

Primary

Measure	Time frame
1. Mortality measured using hospital records, national database and/or contacting patients, their relatives or general practitioners, until the last follow-up control 2. Reoperation on any segment of the aorta for aortic dissection or its related complications, measured using hospital records, national database and/or contacting patients, their relatives or general practitioners, until the last follow-up control	—

Measure

Time frame

1. Mortality measured using hospital records, national database and/or contacting patients, their relatives or general practitioners, until the last follow-up control 2. Reoperation on any segment of the aorta for aortic dissection or its related complications, measured using hospital records, national database and/or contacting patients, their relatives or general practitioners, until the last follow-up control

—

Secondary

Measure	Time frame
1. Stroke or global brain ischemia measured using hospital records during the index hospital stay 2. Acute kidney injury measured using hospital records during the index hospital stay 3. Surgical site infection measured using hospital records during the index hospital stay 4. Reoperation for bleeding measured using hospital records during the index hospital stay 5. Blood transfusion measured using hospital records during the index hospital stay 6. Paraplegia/paraparesis measured using hospital records during the index hospital stay	—

Measure

Time frame

1. Stroke or global brain ischemia measured using hospital records during the index hospital stay 2. Acute kidney injury measured using hospital records during the index hospital stay 3. Surgical site infection measured using hospital records during the index hospital stay 4. Reoperation for bleeding measured using hospital records during the index hospital stay 5. Blood transfusion measured using hospital records during the index hospital stay 6. Paraplegia/paraparesis measured using hospital records during the index hospital stay

—

Countries

Belgium, Czech Republic, England, Finland, France, Germany, Hungary, Italy, Netherlands, Spain, United Kingdom, United States of America

Contacts

Public ContactFausto Biancari

fausto.biancari@hus.fi+393474837339

Outcome results

None listed

Source: ISRCTN (via WHO ICTRP) · Data processed: Feb 4, 2026