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Effectiveness of chemical disinfection on biofilm of relined dentures

Effectiveness of chemical disinfection on biofilm of relined dentures: a randomized clinical trial

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ISRCTN
Registry ID
ISRCTN26594186
Enrollment
45
Registered
2014-09-29
Start date
2011-03-10
Completion date
Unknown
Last updated
2015-01-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Maxillary denture relining Oral Health

Interventions

The patients were randomly divided into three groups (n = 15)
allocation was concealed with the use of the BioStat program. The dentures were cleansed according to three methods: CG (control group) ? brushing with coconut soap and soft toothbrush
PG (perborate group) ? brushing according to previous methods and disinfection with warmed sodium perborate solution (Corega Tabs ? GlaxoSmithKline Brasil Ltda, Rio de Janeiro ? RJ, Brazil) for 5 mi
and ChxG (chlorhexidine group) ? brushing according to CG and disinfection with 2% chlorhexidine digluconate (Arte &Ciência, Farmácia de Manipulação, Araraquara ? SP, Brazil) for 5 minutes once a day

Sponsors

São Paulo State University (UNESP) (Brazil)
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: 1. Age between 50 to 75 years 2. Have attended the School of Dentistry of Araraquara/UNESP 3. Healthy with good manual dexterity whose maxillary dentures required relining

Exclusion criteria

Exclusion criteria: Presence of oral or systemic diseases

Design outcomes

Primary

MeasureTime frame
1. Microbial growth for each type of denture 48 hours after the reline procedure. Swabs were collected 48 hours after the reline procedure (day 0) and at the follow-up time intervals of 7, 15, 30, 90, and 180 days. 2. The surface roughness (Ra-µm) of each denture as measured using a profilometer with a resolution of 0.01 µm, an interval (cut-off length) of 0.8 mm, a transverse length of 2.4 mm, a stylus speed of 0.5 mm s-1, and a diamond stylus tip radius of 5 µm. One operator recorded all measurements, taken immediately after the relining and after 7, 15, 30, 90, and 180 days of treatment.

Countries

Brazil

Outcome results

None listed

Source: ISRCTN (via WHO ICTRP) · Data processed: Feb 4, 2026