Hypertension Circulatory System
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1. Participant is able and willing to provide informed consent. 2. Participant is =20 and =50 years of age. 3. Participant with diagnosis of Hypertension for a minimum of 1 year and up to 5 years. 4. Participant has been on the same class/classes of blood pressure medication for a minimum of 6 months. 4.1. Note: A change in dosage, frequency, or specific medication is acceptable as long as there have been no changes to the class/classes of medications prescribed. 5. Participant is currently prescribed and taking one of the following classes of medications alone or in combination with each other: 5.1. Diuretics (thiazide or thiazide-like) 5.2. ACE Inhibitors 5.3. Angiotensin Receptor Blocker (ARB) 5.4. Beta-blockers 5.5. Ca2+ Channel Blockers 6. Evidence that the participant has regular GP visits and is compliant with medication (i.e., collects prescriptions).
Exclusion criteria
Exclusion criteria: 1. Participant has a diagnosis of secondary hypertension or is pregnant. 2. Participant is currently prescribed and taking any additional class of medication(s) for high blood pressure not included in the list above 3. Participant has Systolic blood pressure >190 or Diastolic blood pressure >120 documented within the six months prior to visit. 4. Participant has co-morbidities such as heart failure, myocardial infarction and renal impairment. 5. Any other reason that the participant is inappropriate for study enrolment in the opinion of the Investigator.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Clinic blood pressure measured using a non-invasive brachial artery blood pressure device (e.g., oscilometric, auscultation) will be obtained by reviewing patient notes. | — |
Secondary
| Measure | Time frame |
|---|---|
| Obtained by reviewing patient notes: 1. Number and types of medications needed to control blood pressure 2. Time to control 3. Number of clinic visits to control 4. Side effects from hypertension therapy 5. Hypertension associated adverse events during treatment 6. Single nucleotide polymorphisms on 11 genes related to blood pressure will be determined from mouth swab samples | — |
Countries
New Zealand