DemDx AI-driven Ophthalmology Triage System clinical evaluation in accident and emergency

Clinical evaluation and implementation of DemDx AI-driven Ophthalmology Triage System (DOTS) in an adult eye casualty accident and emergency (A&E)

Status

Active, not recruiting

Phases

Phase 1

Study type

Observational

Source

ISRCTN

Registry ID

ISRCTN25862260

Enrollment

Registered

2023-08-07

Start date

2023-06-17

Completion date

Unknown

Last updated

2023-10-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Triaging of patients who attend adult eye casualty Eye Diseases

Interventions

The clinical investigation will be a pre-post quasi-experimental study, comparing the triage performance after implementing the AI-driven triage support tool A&E triage pathway to prospective cases us

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: Registered nurses who have completed competency training in triage in adult eye casualty

Exclusion criteria

Exclusion criteria: 1. Nurses who have not completed ophthalmic triage competency training 2. Triage nurses in paediatric eye casualty

Design outcomes

Primary

Measure	Time frame
The proportion of false positive referrals to same-day Eye Casualty A&E appointment or UCC (urgent care clinic, same-week appointments) consultations compared with retrospective data from matched cases in the study site. A false positive is a patient who has been inappropriately referred to same-day Eye Casualty A&E appointment or UCC consultation but who could have been given appropriate advice at triage and safely discharged without a face-to-face consultation. Adjusted relative risk (RR) will be reported. This is a before-and-after study where the triage data will be collected with the intervention for about 3 months and compared with the same period in the previous year. Patient data will be collected at one point during the trial but it will be monitored for 14 days for re-attendance.	—

Measure

Time frame

The proportion of false positive referrals to same-day Eye Casualty A&E appointment or UCC (urgent care clinic, same-week appointments) consultations compared with retrospective data from matched cases in the study site. A false positive is a patient who has been inappropriately referred to same-day Eye Casualty A&E appointment or UCC consultation but who could have been given appropriate advice at triage and safely discharged without a face-to-face consultation. Adjusted relative risk (RR) will be reported. This is a before-and-after study where the triage data will be collected with the intervention for about 3 months and compared with the same period in the previous year. Patient data will be collected at one point during the trial but it will be monitored for 14 days for re-attendance.

—

Secondary

Measure	Time frame
1. In the accuracy sub-study, agreement levels of DOTS for suggesting urgent and non-urgent differential diagnoses will be compared with the diagnoses at discharge 2. Rate of Eye Casualty A&E re-attendance within 14 days (potential false negatives) 3. Patient waiting time compared to pre-intervention as previously reported by the Performance and Information team 4. Cost-effectiveness analysis of intervention using false positive referrals and resource utilisation as compared with pre-intervention data This is a before-and-after study where the triage data will be collected with the intervention for about 3 months and compared with the same period in the previous year. Patient data will be collected at one point during the trial but it will be monitored for 14 days for re-attendance.	—

Measure

Time frame

1. In the accuracy sub-study, agreement levels of DOTS for suggesting urgent and non-urgent differential diagnoses will be compared with the diagnoses at discharge 2. Rate of Eye Casualty A&E re-attendance within 14 days (potential false negatives) 3. Patient waiting time compared to pre-intervention as previously reported by the Performance and Information team 4. Cost-effectiveness analysis of intervention using false positive referrals and resource utilisation as compared with pre-intervention data This is a before-and-after study where the triage data will be collected with the intervention for about 3 months and compared with the same period in the previous year. Patient data will be collected at one point during the trial but it will be monitored for 14 days for re-attendance.

—

Countries

England, United Kingdom

Outcome results

None listed

Source: ISRCTN (via WHO ICTRP) · Data processed: Feb 4, 2026