Arm veins versus contralateral greater saphenous vein for lower extremity bypass reconstruction in patients with absent ipsilateral greater saphenous vein

Arm veins versus contralateral greater saphenous vein for lower extremity bypass reconstruction in patients with absent ipsilateral greater saphenous vein: a randomized trial

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

ISRCTN

Registry ID

ISRCTN25666105

Enrollment

628

Registered

2014-02-12

Start date

2010-06-01

Completion date

Unknown

Last updated

2019-02-11

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Peripheral arterial occlusive disease of the lower extremity Circulatory System

Interventions

Standard vein bypass techniques for lower limb revascularization in patients suffering from peripheral arterial occlusive disease. For Group A patients arm veins (basilic and/or cephal

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: 1. Male or female aged 30 years and over 2. Claudication > 2 months 3. Critical leg ischemia > 2 months 4. Popliteal aneurysm 5. Absent ipsilateral greater saphenous vein 6. Usable arm vein (cephalic and/or basilic vein without signs of sclerosis or thrombosis and with diameter > 2.5 mm verified by preoperative duplex) 7. Usable contralateral greater saphenous vein (without signs of sclerosis or thrombosis and with diameter > 2.5 mm verified by preoperative duplex) 8. Atherosclerosis

Exclusion criteria

Exclusion criteria: 1. Urgent critical leg ischemia (thromboembolic event < 2 months) 2. Absent arm vein (e.g., due to prior operation) 3. Unusable arm vein (due to sclerosis and/or thrombosis and/or small (< 2.5 mm) diameter verified by preoperative duplex) 4. Absent contralateral greater saphenous vein (due to prior coronary bypass, peripheral bypass, vein stripping, trauma, etc) 5. Unusable contralateral greater saphenous vein (due to sclerosis and/or thrombosis and/or small (< 2.5 mm) diameter verified by duplex) 6. Arm veins should be saved for arterio-venous fistula 7. Deep vein thrombosis of the contralateral leg 8. Critical leg ischemia of the contralateral leg 9. Trauma

Design outcomes

Primary

Measure	Time frame
Primary and secondary bypass patency measured at baseline, 1 month, 3 months , 6 months after discharge and then at 6-month intervals for 2 years	—

Secondary

Measure	Time frame
1. Local complications (e.g., surgical site infections) 2. Systemic complications (e.g., myocardial infarction, stroke) 3. Clinical and hemodynamic improvement 4. Limb salvage 5. Survival Measured at baseline, 1 month, 3 months , 6 months after discharge and then at 6-month intervals for 2 years.	—

Countries

Austria

Outcome results

None listed

Source: ISRCTN (via WHO ICTRP) · Data processed: Feb 4, 2026