Effect of chocolate with and without polyphenols on health in type 2 diabetes

Crossover randomised controlled trial studying the effects of chocolate with and without polyphenols in type 2 diabetes

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

ISRCTN

Registry ID

ISRCTN25655161

Enrollment

Registered

2009-09-22

Start date

2007-01-01

Completion date

Unknown

Last updated

2015-01-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Type 2 diabetes Nutritional, Metabolic, Endocrine Non-insulin-dependent diabetes mellitus

Interventions

Subjects were given either 45 g per day of high polyphenol chocolate or low polyphenol chocolate for 2 months. Following 1 month washout they were switched to the other chocolate.

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: 1. Both males and females, ages 18 and above 2. Type 2 diabetes 3. Stable medication

Exclusion criteria

Exclusion criteria: Changes in medication over the past 3 months

Design outcomes

Primary

Measure	Time frame
Lipid profile All outcome measures were measured at baseline, 8 weeks (following intervention 1), 12 weeks (following washout) and 20 weeks (following intervention 2).	—

Secondary

Measure	Time frame
Homeostatic Model Assessment (HOMA) index All outcome measures were measured at baseline, 8 weeks (following intervention 1), 12 weeks (following washout) and 20 weeks (following intervention 2).	—

Countries

United Kingdom

Outcome results

None listed

Source: ISRCTN (via WHO ICTRP) · Data processed: Feb 4, 2026