Fractured Hip Infection Trial: FHIT- low vs. high dose antibiotic impregnated cement in the treatment of patients with fractured neck of femur

Low vs. high dose antibiotic impregnated cement in the treatment of patients with fractured neck of femur: a two arm assessor blinded randomised controlled trial

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

ISRCTN

Registry ID

ISRCTN25633145

Enrollment

848

Registered

2013-03-21

Start date

2008-07-01

Completion date

Unknown

Last updated

2018-11-12

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Fracture of neck of femur / Surgical site infection / orthopaedic Injury, Occupational Diseases, Poisoning Fracture of neck of femur

Interventions

In this pragmatic trial, patients will undergo emergency hip hemiarthroplasty (cemented) using the standard technique of the anaesthetist and the operating surgeon. In addition, the patient will unde

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: All trauma orthopaedic patients (age 18 and over) who require a hip hemiarthroplasty for a fractured neck of femur will be included in the study

Exclusion criteria

Exclusion criteria: Patients under 18

Design outcomes

Secondary

Measure	Time frame
1. Superficial surgical site infection as defined by the Health Protection Agency 2. Length of stay 3. Surgeon grade will be documented as consultant orthopaedic surgeon, specialist trainee or core training doctor. 4. Admission to high dependency unit 5. All complications will be recorded All baseline data will be summarised descriptively by treatment group.	—

Primary

Measure	Time frame
Deep surgical site infection as defined by the Health Protection Agency	—

Countries

United Kingdom

Outcome results

None listed

Source: ISRCTN (via WHO ICTRP) · Data processed: Mar 10, 2026