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Reinforcement of closure of stoma site using a biological mesh – extended follow-up

Extended follow-up of the ROCSS trial

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
ISRCTN
Registry ID
ISRCTN25584182
Enrollment
702
Registered
2022-05-10
Start date
2021-02-01
Completion date
Unknown
Last updated
2024-08-26

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Incisional hernia Surgery

Interventions

There is no intervention if ROCSS-EX as such as it extended follow-up – the intervention under investigation remains the same one as in the original ROCSS trial (Reinforcement of the stoma closure sit

Sponsors

University of Birmingham
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: All participants included in the ROCSS trial are eligible to be included in ROCSS-EX unless they withdrew or did not have their stoma reversed during the duration of the original trial. those participants who have died, only routinely collected data will be used.

Exclusion criteria

Exclusion criteria: Does not meet inclusion criteria

Design outcomes

Primary

MeasureTime frame
Quality of life at 5 to 8 years following closure of stoma site comparing participants who had mesh reinforcement of their abdominal wall with participants that had a standard closure. This will be assessed using the HerQLes tool

Secondary

MeasureTime frame
At 5-8 years follow-up: 1. Participant reported incisional hernia rate 2. Number of hospital visits for any hernia related reason 3. Number of interventional procedures related to the stoma closure site or hernia 4. Longitudinal QoL assessed using EQ-5D 5. Cost analysis for all additional hernia related events

Countries

England, Scotland, United Kingdom

Contacts

Public ContactJames Brown
rocss@trials.bham.ac.uk+44 121 414 9012

Outcome results

None listed

Source: ISRCTN (via WHO ICTRP) · Data processed: Feb 5, 2026