PICSO in NSTEMI

PICSO in NSTEMI registry: Pressure controlled intermittent coronary sinus occlusion in NonST elevation Myocardial Infarction

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

ISRCTN

Registry ID

ISRCTN25579748

Enrollment

Registered

2015-02-04

Start date

2015-01-05

Completion date

Unknown

Last updated

2018-04-30

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Topic: Cardiovascular disease

Interventions

Pressure controlled Intermittent Coronary Sinus Occlusion (PICSO)

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: 1. Ischemic symptoms such as angina pectoris for more than 20 minutes 2. Occurrence of previous symptoms less than 72 hours before enrolment 3. Cardiac troponin levels above the 99th percentile at presentation and 4. Age range: 18-75

Exclusion criteria

Exclusion criteria: 1. Cardiogenic shock 2. STEMI 3. Coronary anatomy ineligible for Coronary Sinus cannulation. 4. Indication for acute bypass surgery 5. Pregnancy 6. Current participation in another study 7. Comorbidity with a life expectancy of less than 6 months 8. Contraindication to cMRI

Design outcomes

Primary

Measure	Time frame
Infarct Size reduction; Timepoint(s): Infarct Size reduction from days 35 after PCI to 4 months post PCI	—

Secondary

Measure	Time frame
Not provided at time of registration	—

Countries

United Kingdom

Outcome results

None listed

Source: ISRCTN (via WHO ICTRP) · Data processed: Feb 4, 2026