Lumbar degenerative disc disease. Musculoskeletal Diseases
Conditions
Interventions
Patients with lumbar degenerative disc disease were randomly assigned to either a PEEK (polyetheretherketone) cage or an autologous cage using the lumbar spinous process and laminae (ACSP). Monosegmen
Sponsors
Xiamen University
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1. Patients aged between 30-70 years 2. Disc pathology requiring surgical intervention for decompression 3. One intended level of interbody fusion between L3 and S1 4. Radiological evidence of instability, spondylolisthesis and the presence of degenerative stenosis, or symptomatic degenerative disc disease 5. Persistent or recurrent low back or leg pain lasting at least 6 months and resulting in a significant reduction of quality of life
Exclusion criteria
Exclusion criteria: 1. Patients need for two or more levels of fusion 2. Active infection 3. Metabolic disease 4. Severe osteoporosis, symptomatic vascular disease 5. Previous spinal surgery other than a lumbar discectomy in L3-L4, L4-L5, or L5-S1 6. Any major psychological problem 7. The combination of degenerative scoliosis and degenerative or isthmic spondylolithesis 8. Morbid obesity 9. Smokers
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Functional outcome was assessed using the Kirkaldy–Willis criteria 3, 6, 12 and 24 months postoperatively and annually thereafter. | — |
Secondary
| Measure | Time frame |
|---|---|
| 1. Visual Analogue Score (VAS) was obtained for low back pain both pre- and postoperatively at 2-year follow-up 2. Radiological assessment was recorded at at 3, 6, 12 and 24 months postoperatively and annually thereafter 3. Fusion status was evaluated by anteroposterior and lateral flexion and extension radiographs | — |
Countries
China
Contacts
Public ContactBin Lin
Outcome results
None listed