HOME FIRST (Home Followed-up by the Infection Respiratory Support Team)

HOME FIRST (Home Followed-up by the Infection Respiratory Support Team): a feasibility study

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

ISRCTN

Registry ID

ISRCTN25542492

Enrollment

200

Registered

2012-10-16

Start date

2011-12-10

Completion date

Unknown

Last updated

2020-03-30

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Respiratory infection, including lower respiratory tract infection, pneumonia and bronchiectasis Respiratory Other acute lower respiratory infections

Interventions

HOME FIRST - Early supported hospital discharge or standard hospital care

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: Patients with any of the following conditions: 1. Pneumonia - community-acquired (CAP) or hospital-acquired (HAP) - pneumonia definition - a series of clinical symptoms with radiological consolidation N.B. All pneumonia CURB-65 scores will be considered but patients with CURB-65 =3 MUST have had at least 24hrs of in-patient observation before recruitment into the study. 2. Acute tracheo-bronchitis & acute bronchitis 3. Non-pneumonic lower respiratory tract infection 4. Influenza with respiratory manifestations 5. Infective exacerbation of bronchiectasis 6. Lung abscess 7. Pneumonia with concomitant COPD (if this service is not provided elsewhere) Patient Suitability: 1. Simple pleural effusions only (if no diagnostic pleural tap performed please discuss) 2. Can manage ADLs with current support (immediate OT/physio/social assessment/care can be arranged prior to discharge (if needed) and continued at home) 3. Able to give fully informed consent 4. Has a phone 5. Age>18yrs old 6. EWS =2 AND SBP>90 (all observations must be stable for 12-24hrs) AND mild confusion only (defined as an 10-point AMTS =7) 7. All observations must be stable for 12-24hrs 8. Improving inflammatory markers (WCC/CRP) 9. Stable or improving U&Es

Exclusion criteria

Exclusion criteria: 1. Acute exacerbations of COPD - infective & non-infective (other services already provided) 2. Patients with CURB-65 >3 admitted92%] - for patients with chronic respiratory illness. All such cases MUST be discussed as oxygen assessment may be needed.

Design outcomes

Primary

Measure	Time frame
Patient acceptability	—

Secondary

Measure	Time frame
1. Safety/mortality 2. Readmission rate 3. Length of stay 4. Total days of care 5. Functional and symptom improvement	—

Countries

United Kingdom

Outcome results

None listed

Source: ISRCTN (via WHO ICTRP) · Data processed: Mar 8, 2026