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Short term oral conjugated linoleic acid supplementation enhanced glycogen synthesis in exercised human skeletal muscle

Conjugated linoleic acid enhanced glycogen synthesis

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ISRCTN
Registry ID
ISRCTN25537986
Enrollment
12
Registered
2013-08-16
Start date
2011-08-01
Completion date
Unknown
Last updated
2015-01-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Sports nutrition and ergogenic aids Nutritional, Metabolic, Endocrine

Interventions

The trial order for the 12 subjects was randomized so that six subjects started with eight weeks CLA trial, while six subjects started with eight weeks placebo trial. Subjects participated in this cr

Sponsors

National Science Council (Taiwan)
Lead Sponsor

Eligibility

Sex/Gender
Male

Inclusion criteria

Inclusion criteria: For the successful completion of the proposed study, twelve male athletes, aged around 20 years will be recruited from National Taichung University and National Taiwan College of Physical Education. All subjects have been participated in regular exercise training at least three years.

Exclusion criteria

Exclusion criteria: Subjects who have never been accept regular exercise training and are smokers will be excluded to participate this study.

Design outcomes

Primary

MeasureTime frame
Glycogen assay: approximately 25 mg of skeletal muscle from the deep portion of the vastus lateralis was dissolved in 1 N KOH at 75°C for 30 minutes. Dissolved homogenate was neutralised by glacial acetic acid and incubated overnight in acetate buffer (0.3 M sodium acetate, pH to 4.8) containing amyloglucosidase (Boehringer Mannheim, Indianapolis, IN). The reaction mixture was neutralised with 1 N NaOH. Samples were then analysed by measuring glucosyl units by the Trinder reaction (Sigma, St. Louis, MO).

Secondary

MeasureTime frame
Protein expressions of GLUT4, p-Akt measured with western blotting

Countries

Taiwan

Outcome results

None listed

Source: ISRCTN (via WHO ICTRP) · Data processed: Feb 4, 2026