Producing heart cells from patients with inherited heart rhythm disorders from skin cells in order to develop new treatments

Use of cardiac myocytes derived from skin fibroblasts to study patients with Inherited Arrhythmia Syndromes (IAS)

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

ISRCTN

Registry ID

ISRCTN25297151

Enrollment

Registered

2015-02-13

Start date

2015-04-01

Completion date

Unknown

Last updated

2018-08-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Inherited Arrhthymia Syndromes Circulatory System Inherited arrhthymia syndromes

Interventions

Skin biopsy in order to derive cardiac cells

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: 1. Confirmed diagnosis of inherited condition OR family member of patient with inherited condition 2. Aged > 18 3. Informed consent available

Exclusion criteria

Exclusion criteria: 1. Unwilling or unable to give informed consent 2. Age <18

Design outcomes

Primary

Measure	Time frame
Derivation of cardiac myocytes from skin fibroblasts obtained from patients affected by inherited arrhythmia syndromes and their family members.	—

Secondary

Measure	Time frame
1. Identification of new genes in patients with inherited arrhythmia syndromes 2. Testing of new treatment strategies for inherited cardiac conditions	—

Countries

United Kingdom

Outcome results

None listed

Source: ISRCTN (via WHO ICTRP) · Data processed: Feb 4, 2026