Leukaemia (acute), lymphoma (non-Hodgkin's) Cancer Leukaemia
Conditions
Interventions
Patients are randomised to one of four treatment arms:
1. Arm A: A single course of cyclophosphamide, vincristine, prednisolone (COP) followed by two courses of chemotherapy with cyclo
Sponsors
Cancer Research UK (CRUK) (UK)
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1. B-large cell, small non-cleaved non-Hodgkin's disease or B-cell leukaemia 2. Stages I-IV 3. Aged over 6 months and under 18 years 4. No previous chemotherapy. Emergency radiotherapy or immunotherapy is permitted 5. No congenital immunodeficiency 6. No prior organ transplantation 7. No previous malignancy of any type 8. No medical contraindications to protocol treatments 9. Patients available for a minimal follow-up of 36 months
Exclusion criteria
Exclusion criteria: Not provided at time of registration
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Not provided at time of registration | — |
Secondary
| Measure | Time frame |
|---|---|
| Not provided at time of registration | — |
Countries
United Kingdom
Outcome results
None listed